Job name:

4OQL chain A

8e511b92-ffb3-4b1e-aab2-d45917f8f4ec
Finished
Electron density map:

Differential EDM:
Models Number of gaps:3 Gap lengths: 16, 6, 4
Model Entanglement Average DOPE-HR (by gap length)
DOPE-HR 1st gap2nd gap3rd gap
Model 1 Non-trivial -43152
Model 2 Non-trivial -42867
Model 3 Non-trivial -43044
Model 4 Non-trivial -43106
Model 5 Non-trivial -42772
Reload
Warning: All models are renumbered - the first residue in the structure has index 1.
Mix & match
None of the models is perfect? By clicking the button below you can download a .pdb file with the currently shown mix of models - for each gap at most one model can be selected. If none of them is checked, the gap will be left as is. Fourth and further gaps (sorted by size) can only come from one of the models.
Pro Tip: Since you provided a structure that contains some crystallographic information you can verify our models using the wwPDB service.
Validity report for the RCSB PDB structure you were repairing can be accessed here
EntanglementHelpKnotProtLassoProtLinkProt
Model Type Knot core Slipknot Lasso Piercing Show
range loop range loop position in JSmol
Model 1 Slipknot S 31 5-114 114-303 -- --
Model 2 Slipknot S 31 4-114 114-305 -- --
Model 3 Slipknot S 31 6-114 114-303 -- --
Model 4 Slipknot S 4131 4-114 114-303 -- --
Model 5 Slipknot S 31 4-114 114-303 -- --
None
Topologies marked by an OK sign () are in accordance with the template topology.
Warning: Entanglement type is assigned automatically - for more complicated topologies there may be some disagreements with manually curated databases.
Model 1
Model 2
Model 3
Model 4
Model 5
DOPE (Discrete Optimized Protein Energy) score per residue. The lower the score, the better.
Since DOPE is calculated against the neighbours of a given amino acid, the scores
can vary between unmoved segments of different models. See here for more information.
Help
PDB
code		 Chain Entanglement
type		 Seq
identity		 Total gap
coverage		 Total gap
identity		 RMSD [Å] Pairwise alignment to the target: gap


1E2J
B
S +31
99.68%
212.50%
212.50%
0.54

..Target: MPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAGSSHAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSGTAVPPQGAEPQSNAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGE
Template: MPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSANITMGMPYAVTDAVLAPHIGGEAGS---PPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAK------RLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSGTAV------PQSNAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGE

1E2K
B
S +31
100.00%
212.50%
212.50%
0.57

..Target: MPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAGSSHAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSGTAVPPQGAEPQSNAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGE
Template: MPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEA---HAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKR----ERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSGTAV------PQSNAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGE

1KI2
B
S +31
99.68%
175.00%
175.00%
0.70

..Target: MPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAGSSHAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLSGTAVPPQGAEPQSNAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGE-
Template: MPTLLRVYIDGPHGMGKTTTTQLLVALG---DIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAGSSHAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQCGGSWREDWGQLS-------------NAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRSMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGEA
Help
PDB
code		 Chain Knot
type		 Gap
coverage		 Gap
identity		 >Target_Sequence: gap

LSGTAVPPQGAEPQSNAGPRPH
1E2J B S +31 62.50% 62.50%

LSGTAV------PQSNAGPRPH
1E2K B S +31 62.50% 62.50%

LSGTAV------PQSNAGPRPH
1KI2 B S +31 25.00% 25.00%

LS-------------NAGPRPH
PDB
code		 Chain Knot
type		 Gap
coverage		 Gap
identity		 >Target_Sequence: gap

GEAGSSHAPPPA
1E2J B S +31 50.00% 50.00%

GEAGS---PPPA
1E2K B S +31 50.00% 50.00%

GEA---HAPPPA
1KI2 B S +31 100.00% 100.00%

GEAGSSHAPPPA
PDB
code		 Chain Knot
type		 Gap
coverage		 Gap
identity		 >Target_Sequence: gap

LVALGSRDDI
1E2J B S +31 100.00% 100.00%

LVALGSRDDI
1E2K B S +31 100.00% 100.00%

LVALGSRDDI
1KI2 B S +31 50.00% 50.00%

LVALG---DI

Models
Similarity profile
Modelling alignment
Raw knot fingerprint matrices:
Model_1
Model_2
Model_3
Model_4
Model_5

Fri Dec  1 09:41:03 2017	JOB CREATED : 8e511b92-ffb3-4b1e-aab2-d45917f8f4ec
Fri Dec  1 17:02:02 2017	STATUS CHANGED : N -> R
Fri Dec  1 17:02:02 2017	INFO : JOB STARTED AT: 2017-12-01 17:02:02.515516
Fri Dec  1 17:02:02 2017	INFO : METHOD: 1
Fri Dec  1 17:02:02 2017	INFO : Building Profile...
Fri Dec  1 17:02:02 2017	INFO : --E-value set to 0.001--
Fri Dec  1 17:13:29 2017	INFO : Homologue pool found...
Fri Dec  1 17:13:29 2017	INFO : Verifying structure sequences of homologues...
Fri Dec  1 17:16:03 2017	INFO : Starting homologue filtering...
Fri Dec  1 17:16:51 2017	INFO : Getting structures from PDB...
Fri Dec  1 17:17:07 2017	INFO : Creating modelling alignment...
Fri Dec  1 17:17:07 2017	INFO : Modelling...
Fri Dec  1 17:23:34 2017	INFO : Model 1 built
Fri Dec  1 17:23:34 2017	INFO : Validating Calpha distances...
Fri Dec  1 17:23:34 2017	INFO : Model 1 distances correct: True
Fri Dec  1 17:23:34 2017	INFO : Modelling...
Fri Dec  1 17:30:21 2017	INFO : Model 2 built
Fri Dec  1 17:30:21 2017	INFO : Validating Calpha distances...
Fri Dec  1 17:30:21 2017	INFO : Model 2 distances correct: True
Fri Dec  1 17:30:21 2017	INFO : Modelling...
Fri Dec  1 17:37:15 2017	INFO : Model 3 built
Fri Dec  1 17:37:15 2017	INFO : Validating Calpha distances...
Fri Dec  1 17:37:15 2017	INFO : Model 3 distances correct: True
Fri Dec  1 17:37:15 2017	INFO : Modelling...
Fri Dec  1 17:44:35 2017	INFO : Model 4 built
Fri Dec  1 17:44:35 2017	INFO : Validating Calpha distances...
Fri Dec  1 17:44:35 2017	INFO : Model 4 distances correct: True
Fri Dec  1 17:44:35 2017	INFO : Modelling...
Fri Dec  1 17:51:56 2017	INFO : Model 5 built
Fri Dec  1 17:51:56 2017	INFO : Validating Calpha distances...
Fri Dec  1 17:51:56 2017	INFO : Model 5 distances correct: True
Fri Dec  1 17:52:37 2017	INFO : Finished modelling
Fri Dec  1 17:52:37 2017	STATUS CHANGED : R -> P
Fri Dec  1 17:52:37 2017	INFO : Checking topology...
Fri Dec  1 17:54:44 2017	INFO : Knot matrices done...
Fri Dec  1 17:56:23 2017	INFO : Some knots found!
Fri Dec  1 17:56:23 2017	INFO : No lassos found...
Fri Dec  1 17:56:23 2017	INFO : Finishing...
Fri Dec  1 17:56:23 2017	STATUS CHANGED : P -> E
Fri Dec  1 17:56:23 2017	ERROR : Error while finishing
Fri Dec  1 17:56:23 2017	STATUS CHANGED : E -> F
GapRepairer | Interdisciplinary Laboratory of Biological Systems Modelling