Job name:

2WXZ chain C

85b17bdd-3492-4f19-9f7e-ab09cc83c52b
Finished
Models Number of gaps:3 Gap lengths: 17, 9, 8
Model Entanglement Average DOPE-HR (by gap length)
DOPE-HR 1st gap2nd gap3rd gap
Model 1 Non-trivial -55233
Model 2 Non-trivial -55054
Model 3 Non-trivial -55075
Model 4 Non-trivial -55066
Model 5 Non-trivial -54941
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Warning: All models are renumbered - the first residue in the structure has index 1.
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EntanglementHelpKnotProtLassoProtLinkProt
Model Type Knot core Slipknot Lasso Piercing Show
range loop range loop position in JSmol
Model 1 Lasso L +3C -- -- 13-132
Model 2 Lasso L +3C -- -- 13-132
Model 3 Lasso L +3C -- -- 13-132
Model 4 Lasso L +3C -- -- 13-132
Model 5 Lasso L +3C -- -- 13-132
None
Topologies marked by an OK sign () are in accordance with the template topology.
Warning: Entanglement type is assigned automatically - for more complicated topologies there may be some disagreements with manually curated databases.
Model 1
Model 2
Model 3
Model 4
Model 5
DOPE (Discrete Optimized Protein Energy) score per residue. The lower the score, the better.
Since DOPE is calculated against the neighbours of a given amino acid, the scores
can vary between unmoved segments of different models. See here for more information.
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PDB
code		 Chain Entanglement
type		 Seq
identity		 Total gap
coverage		 Total gap
identity		 RMSD [Å] Pairwise alignment to the target: gap


2WXW
A
Unknot
63.70%
229.41%
80.47%
1.12

..Target: ------HPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGA-VLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVLDVTLSSPFLFAIYERDSGALHFLGRVDNPQ
Template: SDRVYIHPFHLVIHNESTCEQLAKANAGKPKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDTEDKLRAAMVGMLANFLGFRIYGMHSELWGVVHGATVLSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLALYTPVVLPRSLDF-TELDVAAEKIDRFMQAVTGWKTGCSLMGASVDSTLAFNTYVHFQGKMKGFSLLAEPQEFWVDNSTSVSVPMLSGMGTFQHWSDIQDNFSVTQVPFTESACLLLIQPHYASDLDKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLSNDRIRVGEVLNSIFFELEA------DE-------PEVLEVTLNRPFLFAVYDQSATALHFLGRVANPL

2WXZ
A
Unknot
99.76%
82.43%
82.43%
0.15

..Target: HPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVLDVTLSSPFLFAIYERDSGALHFLGRVDNPQ
Template: HPFHLLYYSKSTCAQ-------TLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFVGFRMYKMLSEAR-VASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVT--------PLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGE-------AQQPGSPEVLDVTLSSPFLFAIYERDSGALHFLGRVDNPQ

2WY0
C
Unknot
84.91%
88.40%
71.41%
0.83

..Target: -----HPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKMRGFSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNPRVGEVLNSILLELQAGEEEQPTESAQQPGSPEVLDVTLSSPFLFAIYERDSGALHFLGRVDNPQ
Template: DRVYIHPFHLLYHNKSTC--------ETLPESTFEPVPIQAKTSPVNEKTLHDQLVLAAEKLEDEDRKRAAQVAMITNFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTT-------PLLQSIVVGLFTAPGFRLKHSFVQSLALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRGFSQLPGVHEFWVDNSISVSVPMISGTGNFQHWSDAQNNFSVTCVPLGERATLLLIQPHCISDLDRVEALIFQ-DLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKLPTLLGAEANLNNIGDTNPRVGEVLNSILLELKAGEEEQP----------EALDVTLSSPFLFAIYEQDSGTLHFLGRVNNPQ

1KCT
A
Unknot
26.93%
171.90%
75.16%
1.67

..Target: HPFHLLYYSKSTCAQLENPSVETLPEPTFEPVPIQAKTSPVDEKTLRDKLVLATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFVESLGPFTPAIFPRSLDLS-TDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQGKM-RGFS-QLTGLHEFWVDNSTSVSVPMLSGTG--NFQHWSDAQNNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQ--HDFLT-WIKNPPPRAIRLTLPQLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNP-RVGEVLNSILLELQAGEEEQPTESA------QQPGS--PEVLDVTLSSPFLFAIYERDSGALHFLGRVDNP--Q
Template: HP------------------------------------------------------------TFNKITPNLAEF-AFSLYRQLAH-QSNSTNIFFSPVSIAAAFAMLSLGAKGDTHDE--------ILEG-LNFNLTEIPEAQIHEGFQELLRTLNQPDSQ--LQLTTGNGLFLSEGLKLVDKFLEDV---KKLYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKL-SSWVLLMKYLG-NATAIFFLP----DEGKLQHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTI----DEKGTEAAGAMFLEAIPMSIPPEV---KFNKPFVFLMIEQNTKSPLFMGKVVNPTQK
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PDB
code		 Chain Knot
type		 Gap
coverage		 Gap
identity		 >Target_Sequence: gap

QAGEEEQPTESAQQPGSPEVLDV
2WXW A Unknot 23.53% 29.41%

EA------DE-------PEVLEV
2WXZ A Unknot 58.82% 58.82%

QAGE-------AQQPGSPEVLDV
2WY0 C Unknot 35.29% 41.18%

KAGEEEQP----------EALDV
1KCT A Unknot 52.94% 94.12%

----DEKGTEAAGAMFLEAIPMSIPPEV---
PDB
code		 Chain Knot
type		 Gap
coverage		 Gap
identity		 >Target_Sequence: gap

LVTQGGSSSQTPLLQ
2WXW A Unknot 44.44% 100.00%

LVAQGRADSQAQLLL
2WXZ A Unknot 11.11% 11.11%

LVT--------PLLQ
2WY0 C Unknot 11.11% 22.22%

LVTT-------PLLQ
1KCT A Unknot 22.22% 77.78%

LRTLNQPDSQ--LQL
PDB
code		 Chain Knot
type		 Gap
coverage		 Gap
identity		 >Target_Sequence: gap

CAQLENPSVETLPE
2WXW A Unknot 12.50% 100.00%

CEQLAKANAGKPKD
2WXZ A Unknot 12.50% 12.50%

CAQ-------TLPE
2WY0 C Unknot 25.00% 25.00%

C--------ETLPE
1KCT A Unknot 0.00% 0.00%

--------------

Models
Similarity profile
Modelling alignment

Fri Dec  1 09:46:56 2017	JOB CREATED : 85b17bdd-3492-4f19-9f7e-ab09cc83c52b
Fri Dec  1 23:31:02 2017	STATUS CHANGED : N -> R
Fri Dec  1 23:31:02 2017	INFO : JOB STARTED AT: 2017-12-01 23:31:02.534406
Fri Dec  1 23:31:02 2017	INFO : METHOD: 1
Fri Dec  1 23:31:02 2017	INFO : Precalculated profile found...
Fri Dec  1 23:31:02 2017	INFO : Homologue pool found...
Fri Dec  1 23:31:02 2017	INFO : Verifying structure sequences of homologues...
Fri Dec  1 23:41:00 2017	INFO : Starting homologue filtering...
Fri Dec  1 23:42:00 2017	INFO : Getting structures from PDB...
Fri Dec  1 23:42:21 2017	INFO : Creating modelling alignment...
Fri Dec  1 23:42:21 2017	INFO : Modelling...
Fri Dec  1 23:52:37 2017	INFO : Model 1 built
Fri Dec  1 23:52:37 2017	INFO : Validating Calpha distances...
Fri Dec  1 23:52:37 2017	INFO : Model 1 distances correct: True
Fri Dec  1 23:52:37 2017	INFO : Modelling...
Sat Dec  2 00:03:00 2017	INFO : Model 2 built
Sat Dec  2 00:03:00 2017	INFO : Validating Calpha distances...
Sat Dec  2 00:03:00 2017	INFO : Model 2 distances correct: True
Sat Dec  2 00:03:00 2017	INFO : Modelling...
Sat Dec  2 00:14:50 2017	INFO : Model 3 built
Sat Dec  2 00:14:50 2017	INFO : Validating Calpha distances...
Sat Dec  2 00:14:50 2017	INFO : Model 3 distances correct: True
Sat Dec  2 00:14:50 2017	INFO : Modelling...
Sat Dec  2 00:26:45 2017	INFO : Model 4 built
Sat Dec  2 00:26:45 2017	INFO : Validating Calpha distances...
Sat Dec  2 00:26:45 2017	INFO : Model 4 distances correct: True
Sat Dec  2 00:26:45 2017	INFO : Modelling...
Sat Dec  2 00:39:13 2017	INFO : Model 5 built
Sat Dec  2 00:39:13 2017	INFO : Validating Calpha distances...
Sat Dec  2 00:39:13 2017	INFO : Model 5 distances correct: True
Sat Dec  2 00:40:11 2017	INFO : Finished modelling
Sat Dec  2 00:40:11 2017	STATUS CHANGED : R -> P
Sat Dec  2 00:40:11 2017	INFO : Checking topology...
Sat Dec  2 00:42:37 2017	INFO : Knot matrices done...
Sat Dec  2 00:42:51 2017	INFO : No knots found...
Sat Dec  2 00:43:02 2017	INFO : Some lassos found!
Sat Dec  2 00:43:02 2017	INFO : Finishing...
Sat Dec  2 00:43:02 2017	STATUS CHANGED : P -> E
Sat Dec  2 00:43:02 2017	ERROR : Error while finishing
Sat Dec  2 00:43:02 2017	STATUS CHANGED : E -> F
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